Human health risk assessment

The objective of risk assessment for human health is to ensure that our ingredients and products are safe for workers and consumers. Part of this evaluation is to anticipate accidents ever, and a possible misuse. For any of the effects on human health, establishing a level of no effect.

The objectives and factors relevant to human health are studied most frequently are: acute toxicity by ingestion or skin contact, skin irritation, eye irritation, possible sensitivity, mutagenicity, reproductive toxicity, neurotoxicity and carcinogenicity.
In assessing risks to human health we rely on two key issues for each goal:

The level of absence of effects on the target. The level or dose of exposure anticipated, calculated for the relevant exposure locations. A comparison of exposure with no effect level is used as an indicator of risk and can be expressed as risk ratio or margin of safety.

Assessment of risks to human health is a gradual process of using short-term tests (acute toxicity by ingestion or contact with skin, eye and skin irritation, mutagenicity and possible sensitivity) and conservative assumptions to reach testing long-term accompanied by more realistic assumptions

The risk ratio or factor of safety is satisfactory. Its exact value depends on the final objectives and the quality of the data. The ratio of risk or safety factor is not satisfactory. This has resulted in the decision not to use the ingredient or limit its use. In the highest degree, the assessment reaches the highest level of realism possible. A ratio of unfavorable risk at this level means that it has reached the end point. In reality, this rarely happens and we do everything possible to identify such problems earlier in the process.